There have been a great many efforts by modern scientists to “find” the TCM meridian system using modern diagnostic tools such as MRI. None of these has been able to point to a single system, such as the nervous system, or circulatory system, which has led many skeptics to shout “Aha! Its all a hoax! Millions of people over thousands of years were simply affected by the placebo effect!” However, this placebo theory falls apart when examining how acupuncture has been effectively used on animals, who have no preconceptions.